124EPIDEMIOLOGICAL EVIDENCE SUGGESTING THE USE OF MORINGA OLEIFERA FOR DECREASING CANCER RISK AND PROCESSES RELATED WITH ITS OCCURRENCEIn the last decade, the use of Moringa oleifera has increased in several countries around the world where this plant is not native, as the United States, Cuba, Guatemala, Honduras, Nicaragua, Venezuela, Colombia, including Mexico, mainly due to its known health benefits and potential pharmacological uses. Nevertheless, the vast majority of the available information about Moringa is provided by suppliers and promoters of “Healthy Food” and “Functional Foods” and it’s of high relevance to separate this information from rigorous scientific evidence. During the years 1991-2000 and 2001-2011, they increased from 18 to 124 publications around the bioactive properties of the compounds found in Moringa oleifera, which describes and support the use of Moringa as an adjunct in the treatment of malnutrition and certain chronic-degenerative and infectious diseases. Besides, particular components of the leaves from Moringa have been extensively studied for the treatment of cancer, having so far evidence of its compounds, in vitro and in vivo analysis and clinical studies. In this review, we focused on the mechanisms of action involved in the protection of Moringa oleifera compounds against the process of cancer.jbheredia@ciad.mxResearch622016Moringa oleifera,Cancer,Bioactive Compounds,Mechanisms of ActionRamon Ignacio Castillo-López,Miguel Angel Angulo-Escalante,Roberto Gutierrez-Dorado,Maria Dolores Muy-Rangel,Josefina Leon-Felix,J. Basilio HerediaDepartment of Antioxidants and Functional Foods. Centro de Investigación en Alimentación y Desarrollo, AC. Carretera a Eldorado Km 5.5. Col. Campo el Diez, Culiacan, Sinaloa, Mexico. CP 80110.,Department of Antioxidants and Functional Foods. Centro de Investigación en Alimentación y Desarrollo, AC. Carretera a Eldorado Km 5.5. Col. Campo el Diez, Culiacan, Sinaloa, Mexico. CP 80110.,Department of Biotechnology, Faculty of Chemical-Biology Sciences. Autonomous University of Sinaloa, Sinaloa, Mexico.,Department of Antioxidants and Functional Foods. Centro de Investigación en Alimentación y Desarrollo, AC. Carretera a Eldorado Km 5.5. Col. Campo el Diez, Culiacan, Sinaloa, Mexico. CP 80110.,Department of Antioxidants and Functional Foods. Centro de Investigación en Alimentación y Desarrollo, AC. Carretera a Eldorado Km 5.5. Col. Campo el Diez, Culiacan, Sinaloa, Mexico. CP 80110.,Department of Antioxidants and Functional Foods. Centro de Investigación en Alimentación y Desarrollo, AC. Carretera a Eldor