An significant stage in the manufacture of drugs for the extraction of chemical leads and the purity of raw drugs is the extraction process. Herbs are the origins of chemical components responsible for the complex functions of ownership, such as antioxidant function, etc. Extraction is a crucial step in the preservation of the raw drug's consistency and is of multiple forms. Both have their own benefits and drawbacks with regard to the efficiency of the extraction and the quantity of solvent used. Tribulus terrestris is a medicinal plant in South India, known to have many chemical components. A significant number of flavonoids are considered to be responsible for antioxidant activity. Plant aerial parts have been useful in handling many diseases, and chemical elements are known to be effective in other cases. Tribulus terrestris aerial parts have been extracted using ethanol and chloroform and three extraction methods. Ultrasound extraction was the best method of extraction and the best solvent for the extraction of flavonoids was found to be ethanol.