In the present research work two medicinal plants of Pakistan were evaluated for their therapeutic potential and presence of secondary metabolites. The whole plant of Phyla nodiflora revealed the presence of alkaloids, glycosides, flavonoids, tannins, terpenoids and saponins while the bark of Pterospermum acerifolium revealed the presence of glycosides, flavonoids, saponins, tannins and terpenoids. Dichloromethane and methanol extracts of selected medicinal plants were studied for antibacterial and anti-inflammatory potential. Dichloromethane extracts of plants exhibited excellent antibacterial activity towards Salmonella typhi and Staphylococcus aureus. Salmonella typhi is responsible for causing typhoid fever and Staphylococcus aureus causes skin and soft tissues infections. Methanol extracts of both plants exhibited moderate anti-inflammatory activity.