ANTIBACTERIAL ACTIVITY OF PARAHEMIONITIS CORDATA (ROXB. EX HOOK. & GREV.) FRASER-JENK. TOWARDS PATHOGENIC CUTANEOUS BACTERIA
B. Ramya Sree
Department of Biotechnology, Sree Vidyanikethan Engineering College, Tirupati
Jyothi M. Joy
Department of Pharmacognosy, Sree Vidyanikethan College of Pharmacy, Tirupati
Parahemionitis cordata, a medicinal pteridophyte was evaluated for its antibacterial potential and phytochemical contents in various solvent extracts of the plant in the gradation of increase in polarity towards bacterial species involved in skin diseases in human beings. Antibacterial activity was evaluated by disc diffusion method. The results indicated that the plant exhibited antibacterial activity in methanol extract. The methanol extract of the plant showed higher level of activity towards Pseudomonas aeruginosa, a resistant strain towards amoxicillin and chloramphenicol. Pseudomonas aeruginosa is often encountered in nosocomial infections. Polar compounds extracted during methanolic extraction and were responsible for antibacterial activity. Petroleum ether and water extracts did not show any antibacterial activity towards any of the tested organisms. The presence of flavonoids and phenols common in acetone and methanol extract. Flavonoid and phenol content in methanol extract of the plant may be one of the reasons for their antibacterial activity. Methanolic extract of the plant exhibited minimum inhibitory concentration as 50mg/ml and minimum bactericidal concentration as 50mg/ml towards Pseudomonas aerogenosa.
5 , 1 , 2015
7 - 10