EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF MACARANGA PELTATA ROXB
B. Ramya Sree
Department of Biotechnology, Sree Vidyanikethan Engineering College, Tirupati
Jyothi M. Joy
Department of Pharmacognosy, Sree Vidyanikethan College of Pharmacy, Tirupati
The petroleum ether extract of Macaranga peltata Roxb. was evaluated for anti-inflammatory activity at the doses of 200 and 400 mg/kg body weight. Carrageenan induced paw edema in rats, which is an acute model used to assess anti-inflammatory activity. The extract has inhibited paw edema in dose related manner. Further the acute toxicity study of the extract had shown no sign of toxicity up to a dose level of 2000mg/kg body weight and thus the extract of Macaranga peltata Roxb. possess significant anti-inflammatory activities.
3 , 1 , 2013
36 - 39