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Issn  2249-7579
e Issn  2249-7579
Publisher JOURNAL OF PHARMACEUTICAL BIOLOGY

PHYTOCHEMICAL SCREENING AND BIOLOGICAL POTENTIAL OF PHYLA NODIFLORA (VERBENACEAE) AND PTEROSPERMUM ACERIFOLIUM (STERCULIACEAE)

B. Ramya Sree
Department of Biotechnology, Sree Vidyanikethan Engineering College, Tirupati
Jyothi M. Joy
Department of Pharmacognosy, Sree Vidyanikethan College of Pharmacy, Tirupati

Autoimmune diseases ,autoantibodies ,Antimicrobial Peptides ,

In the present research work two medicinal plants of Pakistan were evaluated for their therapeutic potential and presence of secondary metabolites. The whole plant of Phyla nodiflora revealed the presence of alkaloids, glycosides, flavonoids, tannins, terpenoids and saponins while the bark of Pterospermum acerifolium revealed the presence of glycosides, flavonoids, saponins, tannins and terpenoids. Dichloromethane and methanol extracts of selected medicinal plants were studied for antibacterial and anti-inflammatory potential. Dichloromethane extracts of plants exhibited excellent antibacterial activity towards Salmonella typhi and Staphylococcus aureus. Salmonella typhi is responsible for causing typhoid fever and Staphylococcus aureus causes skin and soft tissues infections. Methanol extracts of both plants exhibited moderate anti-inflammatory activity.

5 , 3 , 2015

230 - 234